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| Size | 100ug, 1MG |
|---|---|
| Isotype | IgG1, kappa |
| Brand | ProteoGenix |
| Product type | Primary Antibodies |
| Clonality | Monoclonal Antibody |
| Expression system | XtenCHO |
| Applications | Elisa, WB |
| Product name | Dargistotug Biosimilar - Anti-VSTM3 mAb - Research Grade |
|---|---|
| Species | Homo sapiens |
| Expression system | XtenCHO |
| Purity | >90% by SDS-PAGE. |
| Buffer | 0.01M PBS, pH 7.4. |
| Delivery condition | Blue ice (+4°C) |
| Delivery Time | 3-5 days if in stock; 3-5 weeks if production needed |
| Storage condition | 4°C for short term; -20°C for long term |
| Brand | ProteoGenix |
| Aliases /Synonyms | anti-VSTM3, TIGIT, V-set and transmembrane domain-containing protein 3, VSIG9, V-set and immunoglobulin domain-containing protein 9, T-cell immunoreceptor with Ig and ITIM domains |
| Reference | PX-TA2050 |
| Note | For research use only. Not suitable for clinical or therapeutic use. |
| Isotype | IgG1-kappa |
| Clonality | Monoclonal Antibody |
Dargistotug Biosimilar – Anti-VSTM3 mAb – Research Grade is a novel monoclonal antibody (mAb) that has been developed as a potential therapeutic agent for the treatment of various diseases. This biosimilar is a highly specific and potent antibody that targets the V-set and transmembrane domain-containing protein 3 (VSTM3), which is a cell surface protein involved in various cellular processes. In this article, we will discuss the structure, activity, and potential applications of Dargistotug Biosimilar – Anti-VSTM3 mAb – Research Grade.
Dargistotug Biosimilar – Anti-VSTM3 mAb – Research Grade is a recombinant, fully humanized IgG1 monoclonal antibody. It is composed of two heavy chains and two light chains, each consisting of a variable region and a constant region. The variable regions are responsible for binding to the target protein, VSTM3, while the constant regions determine the antibody’s effector functions. The amino acid sequence of Dargistotug Biosimilar – Anti-VSTM3 mAb – Research Grade is highly similar to the reference antibody, making it a suitable biosimilar.
Dargistotug Biosimilar – Anti-VSTM3 mAb – Research Grade has been shown to specifically bind to VSTM3 with high affinity. This binding leads to the inhibition of VSTM3 signaling, which is involved in various cellular processes such as cell growth, survival, and migration. By targeting VSTM3, Dargistotug Biosimilar – Anti-VSTM3 mAb – Research Grade has the potential to modulate these processes and potentially treat diseases that are associated with dysregulated VSTM3 signaling.
Dargistotug Biosimilar – Anti-VSTM3 mAb – Research Grade has shown promising results in pre-clinical studies as a potential therapeutic agent for various diseases. Some of the potential applications of this biosimilar are discussed below:
1.
VSTM3 has been found to be overexpressed in various types of cancer, including breast, lung, and colon cancer. By targeting VSTM3, Dargistotug Biosimilar – Anti-VSTM3 mAb – Research Grade has the potential to inhibit cancer cell growth and survival, making it a potential treatment option for these types of cancer.
2. Inflammatory Diseases VSTM3 has also been implicated in inflammatory diseases, such as rheumatoid arthritis and inflammatory bowel disease. By inhibiting VSTM3 signaling, Dargistotug Biosimilar – Anti-VSTM3 mAb – Research Grade has the potential to reduce inflammation and alleviate symptoms associated with these diseases.
3. Autoimmune Diseases VSTM3 has been shown to be involved in the development of autoimmune diseases, such as multiple sclerosis and lupus. By targeting VSTM3, Dargistotug Biosimilar – Anti-VSTM3 mAb – Research Grade has the potential to modulate the immune response and potentially treat these diseases.
4. Other Diseases Apart from the above-mentioned diseases, VSTM3 has also been implicated in other conditions, such as cardiovascular diseases and neurological disorders. Darg
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