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| Size | 100ug |
|---|---|
| Brand | ProteoGenix |
| Product type | Primary Antibodies |
| Applications | Block |
| Product name | Valziflocept Biosimilar - Anti-IgG fusion protein - Research Grade |
|---|---|
| Uniprot ID | IgG |
| Delivery condition | Blue ice (+4°C) |
| Delivery lead time in business days | 3-5 days if in stock; 3-5 weeks if production needed |
| Storage condition | 4°C for short term (1 week), store at -20°C to -80°C for long term(1 year); Avoid repeated freeze-thaw cycles |
| Brand | ProteoGenix |
| Aliases /Synonyms | Anti-IgG, Anti-IGHG, Anti-IgG Fc fragment, BAX 1810, BAX-1810, FcγRIIb, Human soluble Fc-gamma receptor IIb, SHP 652, SHP-652, SM-101 |
| Isotype | Fc.Gamma.RIIb Receptor (Human Soluble Extracellular Fragment) |
| Clonality | Monoclonal Antibody |
| Protein Name | IgG |
Valziflocept Biosimilar is a novel anti-IgG fusion protein that has gained significant attention in the field of biopharmaceuticals. This research grade protein is a biosimilar of the original Valziflocept, which is a promising therapeutic agent for various autoimmune and inflammatory diseases. In this article, we will delve into the structure, activity, and potential applications of Valziflocept Biosimilar, highlighting its role as an antibody and therapeutic target.
Valziflocept Biosimilar is a fusion protein composed of two components – an antibody fragment and a therapeutic protein. The antibody fragment is derived from the variable region of a humanized monoclonal antibody, while the therapeutic protein is an engineered version of a cytokine or growth factor. These two components are linked together by a flexible linker, allowing for the fusion protein to maintain its structural integrity and function.
The antibody fragment in Valziflocept Biosimilar targets the Fc region of IgG, a key player in immune response and inflammation. This binding specificity allows for targeted delivery of the therapeutic protein to sites of inflammation, reducing the risk of off-target effects. The therapeutic protein component can be chosen based on the specific disease being targeted, making Valziflocept Biosimilar a versatile and customizable treatment option.
Valziflocept Biosimilar exerts its activity through two mechanisms – inhibition of IgG function and delivery of therapeutic protein. By binding to the Fc region of IgG, the fusion protein blocks its interaction with immune cells and other molecules, thereby inhibiting pro-inflammatory responses. This activity is particularly beneficial in autoimmune diseases where excessive IgG activity contributes to tissue damage.
Additionally, the therapeutic protein component of Valziflocept Biosimilar exerts its own anti-inflammatory or regenerative effects. For example, a fusion protein containing a cytokine such as interleukin-10 can suppress inflammation, while a fusion protein containing a growth factor like epidermal growth factor can promote tissue repair. This dual mechanism of action makes Valziflocept Biosimilar a potent and effective treatment option for a range of diseases.
Valziflocept Biosimilar has shown promising results in preclinical studies for various autoimmune and inflammatory diseases, including rheumatoid arthritis, multiple sclerosis, and psoriasis. Its targeted delivery and dual mechanism of action make it a potential alternative to traditional therapies that often have limited efficacy and significant side effects.
Moreover, Valziflocept Biosimilar has the potential to be used in combination with other treatments, such as disease-modifying anti-rheumatic drugs (DMARDs) or biologic therapies, to enhance their effectiveness. This makes it a valuable addition to the current treatment options for these diseases.
In addition to its therapeutic applications, Valziflocept Biosimilar also has potential as a research tool. Its ability to selectively block IgG function can aid in studying the role of IgG in various diseases, while its customizable nature allows for the development of disease-specific fusion proteins for targeted research.
In summary, Valziflocept Biosimilar is a promising anti-IgG fusion protein with a unique structure and dual mechanism of action. Its targeted delivery and customizable nature make it a versatile treatment option for autoimmune and inflammatory diseases. With ongoing research and clinical trials, Valziflocept Biosimilar has the potential to revolutionize the treatment of these diseases and improve patient outcomes.
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