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Recombinant Human STX3 Protein, N-His

Reference: ARO-P12386
Size

100ug

Brand

Arovia

Product type

Recombinant Proteins

Product nameRecombinant Human STX3 Protein, N-His
Origin speciesHuman
Expression systemProkaryotic expression
Molecular weight30.18 kDa
BufferLyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
FormLiquid
Delivery conditionDry Ice
Delivery lead time in business days3-5 days if in stock; 3-5 weeks if production needed
Storage condition4°C for short term (1 week), -20°C or -80°C for long term (avoid freezing/thawing cycles; addition of 20-40% glycerol improves cryoprotection)
BrandArovia
Host speciesEscherichia coli (E.coli)
Fragment TypeIle26-Ile265
Aliases /SynonymsSTX3A, Syntaxin-3, STX3
ReferenceARO-P12386
NoteFor research use only.

Description of Recombinant Human STX3 Protein, N-His

Introduction

Recombinant proteins are proteins that are produced in a laboratory setting through the use of genetic engineering techniques. These proteins are used in various fields, including medicine, biotechnology, and research. One such protein is the Recombinant Human STX3 Protein, which has gained attention for its unique structure, activity, and potential applications.

Structure of Recombinant Human STX3 Protein

The Recombinant Human STX3 Protein is a member of the soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) family. It is a 32 kDa protein that is composed of 290 amino acids. The protein has a conserved SNARE domain, which is responsible for its activity as a fusion protein. It also contains a transmembrane domain that allows it to interact with other proteins and cellular membranes.

Activity of Recombinant Human STX3 Protein

The main function of the Recombinant Human STX3 Protein is to mediate the fusion of intracellular vesicles with the plasma membrane. This process is essential for various cellular functions, including neurotransmitter release, hormone secretion, and protein trafficking. The protein works by forming a complex with other SNARE proteins, including SNAP-25 and VAMP, to promote membrane fusion. This activity is crucial for maintaining proper cellular communication and homeostasis.

Applications of Recombinant Human STX3 Protein

The unique structure and activity of the Recombinant Human STX3 Protein make it a valuable tool in various applications. One of the most significant applications is in the study of vesicle trafficking and membrane fusion. Researchers use this protein to investigate the molecular mechanisms involved in these processes and to understand the role of SNARE proteins in cellular communication.

In addition to its research applications, the Recombinant Human STX3 Protein also has potential therapeutic uses. Studies have shown that this protein plays a crucial role in neurotransmitter release, making it a potential target for neurological disorders such as Parkinson’s disease and epilepsy. Furthermore, the protein has been found to be involved in insulin secretion, making it a potential target for diabetes treatment.

Another potential application of Recombinant Human STX3 Protein is in the development of vaccines. The protein has been identified as an antigen, meaning it can stimulate an immune response in the body. This makes it a potential candidate for vaccine development against diseases caused by pathogens that use membrane fusion as a means of entry into cells.

Conclusion

In summary, the Recombinant Human STX3 Protein is a unique protein with a crucial role in cellular communication. Its structure, activity, and potential applications make it a valuable tool in various fields, including research and medicine. As further research is conducted, the potential uses of this protein are likely to expand, making it an exciting area of study in the field of recombinant proteins.

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