Europe: 5-7 working days
USA & Canada: 7-10 working days
Rest of the world: 5-12 working days
Storage condition
4°C for short term (1 week), -20°C or -80°C for long term (avoid freezing/thawing cycles; addition of 20-40% glycerol improves cryoprotection)
Brand
ProteoGenix
Host species
Insect
Applications
ELISA,WB
Fragment Type
Met1~Pro663
Protein Accession
Q9UM07
Spec:Entrez GeneID
23569
Spec:NCBI Gene Aliases
PAD; PAD4; PDI4; PDI5; PADI5
NCBI Reference
Q9UM07
Aliases /Synonyms
PAD4, PADI5, PDI5,HL-60 PAD,Peptidylarginine deiminase IV,Protein-arginine deiminase type IV
Reference
PX-P4886
Note
For research use only
Description of Protein-arginine deiminase type-4(PADI4)
General Information about Mouse PAD4 (PADI4)
PADI4 gene may play a role in granulocyte and macrophage development leading to inflammation and immune response. PAD4 is mainly expressed in granulocytes, monocytes and CD34+ stem cells. Protein arginine deiminase type-4 was initially cloned from the HL-60 cell line (human promyelocytic leukemia cells). Protein arginine deiminase type-4 may play a role in granulocyte and macrophage development leading to inflammation and immune response. The PADI4 single-nucleotide polymorphism (SNP) and haplotypes were associated with rheumatoid arthritis susceptibility.
Recently, PAD4 has also been found in a variety of malignant tumors and implies its potential roles in tumor genesis.
Eukaryote expression systems and more specifically Insect cells are used at ProteoGenix to produce mouse PAD4 recombinant protein with appropriate post translational modifications.
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