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Anti-DNA-RNA Hybrid Antibody(S9.6)

Reference: ARO-A14575
size

100ug

Isotype

IgG2a, kappa

Brand

ProteoGenix

Applications

IF, IP, SPR

Host Species

Mouse

Clonality

Monoclonal Antibody

Target species

Anti-General Monoclonal Antibody

Product nameAnti-DNA-RNA Hybrid Antibody(S9.6)
Form0.01M PBS, pH 7.4.
Delivery conditionBlue ice (+4°C)
Storage condition4°C for short term (1 week), store at -20°C to -80°C for long term(1 year); Avoid repeated freeze-thaw cycles
BrandProteoGenix
Host speciesMouse
ReactivityGeneral
ReferenceARO-A14575
IsotypeIgG2a, kappa
ClonalityMonoclonal Antibody
PurificationProtein A or G purified from cell culture supernatant.
ImmunogenDNA-RNA Hybrid
Target speciesAnti-General Monoclonal Antibody

Description of Anti-DNA-RNA Hybrid Antibody(S9.6)

Introduction

Anti-DNA-RNA Hybrid Antibody (S9.6) is a monoclonal antibody that specifically recognizes and binds to DNA-RNA hybrids. This antibody has been extensively studied and has shown promising potential as a therapeutic target and a valuable tool for research use. In this article, we will discuss the structure, activity, and applications of Anti-DNA-RNA Hybrid Antibody (S9.6).

Structure of Anti-DNA-RNA Hybrid Antibody (S9.6)

Anti-DNA-RNA Hybrid Antibody (S9.6) is a monoclonal antibody that is produced by hybridoma cells. It is composed of two heavy chains and two light chains, each with a variable region and a constant region. The variable region is responsible for binding to the DNA-RNA hybrid, while the constant region determines the antibody’s effector functions.

The crystal structure of Anti-DNA-RNA Hybrid Antibody (S9.6) has been determined, revealing the binding site for the DNA-RNA hybrid. The antibody has a unique structure with a long, protruding loop that specifically recognizes the DNA-RNA hybrid structure. This loop is essential for the antibody’s specificity and high affinity for DNA-RNA hybrids.

Activity of Anti-DNA-RNA Hybrid Antibody (S9.6)

Anti-DNA-RNA Hybrid Antibody (S9.6) is a highly specific and sensitive antibody that binds to DNA-RNA hybrids with high affinity. It has been shown to recognize both DNA-RNA hybrids in vitro and in vivo, making it a valuable tool for studying these structures.

The antibody’s binding to DNA-RNA hybrids leads to the formation of immune complexes, which can be detected by various techniques such as ELISA, immunofluorescence, and immunoprecipitation. This allows for the quantification and visualization of DNA-RNA hybrids in different biological samples.

Moreover, Anti-DNA-RNA Hybrid Antibody (S9.6) has been shown to have therapeutic potential in various diseases. It has been reported to inhibit the growth of cancer cells by binding to DNA-RNA hybrids and inducing cell death. This makes it a promising candidate for cancer therapy.

Applications of Anti-DNA-RNA Hybrid Antibody (S9.6)

Anti-DNA-RNA Hybrid Antibody (S9.6) has a wide range of applications in both research and therapeutic settings. Some of the key applications include:

1. Research Use

Anti-DNA-RNA Hybrid Antibody (S9.6) is a valuable tool for studying DNA-RNA hybrids in different biological samples. It has been used in various research studies to investigate the role of DNA-RNA hybrids in different cellular processes, such as transcription, DNA repair, and immune response.

The antibody has also been used to study the presence and distribution of DNA-RNA hybrids in different diseases, such as cancer, autoimmune disorders, and neurodegenerative diseases. Its high specificity and sensitivity make it a reliable tool for detecting and quantifying DNA-RNA hybrids in complex biological samples.

2. Therapeutic Target

The unique structure and high specificity of Anti-DNA-RNA Hybrid Antibody (S9.6) make it a potential therapeutic target for various diseases. As mentioned earlier, it has shown promising results in inhibiting cancer cell growth, making it a potential candidate for cancer therapy.

Moreover, DNA-RNA hybrids have been implicated in various autoimmune disorders, and Anti-DNA-RNA Hybrid Antibody (S9.6) has the potential to be used as a targeted therapy for these diseases. Further research is needed to fully understand the therapeutic potential of this antibody.

Conclusion

In summary, Anti-DNA-RNA Hybrid Antibody (S9.6) is a highly specific and sensitive antibody that binds to DNA-RNA hybrids. Its unique structure and high affinity make it a valuable tool for studying these structures and their role in different biological processes and diseases.

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