Antigen design services

Get antibodies—no matter your antigen!

All antigen types are supported to fit your project needs, with precise design and optimization tailored to your specific application:

• Peptides: Custom-designed for high immunogenicity, suitable for both antibody discovery and vaccine development.
• Soluble proteins: Optimized for expression and functionality, ensuring structural integrity for diagnostic or therapeutic purposes.
• Membrane proteins: Engineered to preserve native conformations, essential for functional assays and therapeutic development.
• Small molecules: Designed to bind specifically to target sites, playing a key role in drug discovery and diagnostics.
• DNA: Synthesized and optimized for gene therapy or as antigens in DNA-based vaccines.
• Cells: Tailored to specific immune responses or as models for cancer and autoimmune research.
• Antibodies (anti-idiotype antibodies): Developed for targeted applications, including cancer immunotherapy or autoimmune disease treatment.

Optimize your antigen to maximize antibody success

Antigen design plays a decisive role in the success of antibody development—regardless of the application. A poorly designed antigen can lead to low-affinity, non-specific, or non-functional antibodies, resulting in weak diagnostic performance or failed therapeutic development.
At ProteoGenix, our scientists take a strategic, data-driven approach to antigen design. Your antigen is tailored to the final use—diagnostic assay or therapeutic candidate—while keeping in mind your budget and technical constraints.

If your antigen is a protein:

• Identify the most suitable region of the protein for your application—focusing on epitope accessibility, in silico immunogenicity prediction, and the antibody discovery platform selected (e.g., hybridoma, phage display, single B cell).
• Perform codon optimization to match your chosen expression system.
• Express both soluble and membrane proteins in their native conformation to preserve structural integrity and antigenicity—critical for both accurate diagnostics and functional therapeutics.

Learn more about Protein production services

If your antigen is a peptide:

• Synthesize it at the best value on the market.
• Conjugate it to a carrier protein to boost immunogenicity, maximizing the chances of generating high-quality antibodies for your downstream applications.

Discover more about Custom peptide synthesis