Anti-RBD-5 antibody (Imdevimab)

Reference: PTXCOV-A553



Product type


Description of Anti-RBD-5 antibody (Imdevimab)

General information on Anti-RBD-5 antibody

The anti-CoV-RBD antibody is an anti-SARS-CoV-2 antibody with potential neutralizing activity. By screening its receptor-binding domain (RBD), extensive library of COVID-19 antibodies (LiAb-SFCOVID-19 *) identify the new coronavirus. Variants produced in IgG format have shown stable stability when expressed in XtenCHO ™ (transient expression system based on the created cell line) and consistently provide high and consistent amounts.
In an ELISA (enzyme-linked immunosorbent assay) plate, the specificity and affinity of the IgG antibody were tested against the purified and recombinant form of RBD. Furthermore, the SARS-CoV-2 alternative virus neutralization test (sVNT) indirectly confirmed the neutralization ability. This test is designed to quickly and accurately detect the ability of antibody variants to block the interaction between RBD and specific human receptors. ACE2.
Since the beginning of the pandemic, many studies have confirmed the therapeutic potential of SARS-CoV-2 NAb (neutralizing antibody). The reason RBD takes precedence over other SARS-CoV-2 domains is its key role in the emergence of viral infections. By preventing this important interaction, the researchers hope to halt the development of the disease. Antibody therapy also shows unique advantages over small molecules in the treatment of COVID-19. In fact, most antiviral medications suppress the immune response, which generally delays the clearance of virus particles from the patient. In contrast, antibody therapy further engages and activates the individual’s immune system, resulting in a synergy between the blocking activity of the antibodies and a faster and safer removal of virus pathogens. In this case, the investigation of neutralizing antibodies (such as anti-CoV-RBD (E4)) can help to investigate the progression of the disease and the response of the body to specific therapies.

Product nameAnti-RBD-5 antibody (Imdevimab)
Expression systemMammalian
Molecular weight150kDa
BufferPBS, pH7,5
Delivery conditionDry ice
Storage condition4°C for short term; -20°c or -80°C for long term
Aliases /SynonymsREGN10987
Related ProductsRBD Domain,SARS-CoV-2 RBD of Spike protein, N501Y – B 1.1.7 lineage – UK Alpha Variant,RBD Domain,SARS-CoV-2 RBD of Spike protein, N501Y – B 1.1.7 lineage – UK Alpha Variant,SARS-CoV-2 RBD of Spike protein, K417N, E484K, N501Y – B.1.351 lineage – SA Beta Variant,SARS-CoV-2 RBD of Spike protein, K417T, E484K, N501Y – lineage B. – BR Gamma Variant,SARS-CoV-2 RBD of Spike protein, E484K
NoteFor research use only. Not suitable for in vitro diagnostic and human use.
ClonalityMonoclonal Antibody


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