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As a world leader in custom gene synthesis, ProteoGenix has offered high quality services at affordable prices for the last 15 years and gathers all the following advantages over competition:
- Expertise: Dozens of thousands of gene synthesis delivered during the past 15 years
- Speed: 99% of gene synthesis delivered on time and faster than the average market lead times
- Price: Best prices available on the market
- Design & Advices: PhDs experts in protein production are available to help design your constructions the best way
- Confidentiality: A high level of confidentiality is ensured when working with ProteoGenix as we understand the sensitivity of this information for you research
Only ATGC allowed in the sequence.Spaces are automatically removed.
Your gene contains low (if <30%) or high (if >70%) GC content and cannot be considered as a standard gene. A sequence optimization may be required. Click the submit button below to send all information provided above in order for us to contact you quickly and let you know how we can proceed with your sequence synthesis.
Thank you for your visit. An account manager will contact you within the next 24/48h with a quotation and instructions on how to proceed with your Gene Synthesis project.
Your sequence is > to 5000 BP so we can't calculate the price. An account manager will contact you within the next 24/48h with a quotation and instructions on how to proceed with your Gene Synthesis project.
Do you need us to add a start codon (ATG)?
Do you need us to add a stop codon?
5’ restriction site:
Enzyme?
Sequence?
3’ restriction site:
Enzyme ?
Most amino acids are encoded by multiple codons that are called synonymous codons. However, specific codons are used more often than others during gene translation. This phenomenon is called the codon usage bias and is species specific. So, as a result of the redundancy of the genetic code, rare codons can be replaced by codons that are more abundant in the genes of the host organism, without changing the amino acid sequence of the protein, per se. ProteoGenix’s Codon Optimization Tool leverages a codon bias strategy and additional parameters like GC content, repetitive sequences, avoiding restriction sites and mRNA secondary structure. Codon optimization makes DNA synthesis easier and improves recombinant protein production yields when expression is done in heterologous hosts. We therefore strongly recommend to let us optimize the sequence.
Would you like us to optimize your DNA sequence?
The encoded amino acid sequence will remain 100% identical. We strongly recommend such an optimization for easier synthesis and protein expression.
Host expression organism:
Optional: secondary host
Optimization start position:
Optimization end position:
ORF start position:
ORF end position:
Restriction sites to avoid: (press ctrl and clic on the sites)
Restriction sites to keep: (press ctrl and clic on the sites)
Standard Service :
Rush Service :
Rush service is available for genes <1 500bp only. So it cannot apply to your DNA sequence.
We strongly recommend to clone the fragment into a plasmid for DNA sequences >200bp.
Choose the type of vector in which you would like us to clone your DNA sequence:
None
Amplification Vector
Expression Vector
Vector provided by the visitor
Please also send the gene in the following amplification vector:
This option can save material transfer time and cost and will make your future ordering easier
Standard delivery : 4µg of cloned gene or 500ng of DNA sequence
Custom plasmid preparation:
Do you need Mutagenesis?
Starting Sequence
Mutated Sequence
Mutations highlighted in purple. Only ATGC allowed in the sequence.Spaces are automatically removed.
Have you ordered this gene from us previously?
No
Yes
Please select the country of delivery so that we can send you the quotation including shipping costs.
Deliverable & Guarantees*Duration is predicted and indicative and can vary depending on several factors
Gene optimization tool
Sequence 100% guaranteed
4µg of cloned gene or 500ng of DNA sequence
No gene, no fee
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